Google scholar profile
Peer-reviewed articles
Click on the links to download PDF / enter page for the full-text of the paper.
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Li HH, Guo AN, Salgado M, Saez JC, Lau CG#. The novel connexin hemichannel inhibitor D4 produces rapid antidepressant-like effects in mice. Journal of Neuroinflammation, 2023, https://jneuroinflammation.biomedcentral.com/articles/10.1186/s12974-023-02873-z.
香港城市大学刘俊宇团队发现连接蛋白半通道抑制剂D4的抗抑郁样作用
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Guo AN, Zhang HQ, Li HH, Chiu A, Garcia C, Lagos CF, Saez JC#, Lau CG#. Inhibition of connexin hemichannels alleviates neuroinflammation and hyperexcitability in temporal lobe epilepsy. Proc Natl Acad Sci USA, https://www.pnas.org/doi/10.1073/pnas.2213162119, 2022.
CityU neuroscientists discover a new drug candidate for treating epilepsy
刘俊宇团队揭示连接蛋白半通道在减轻颞叶癫痫发病过程中的神经炎症和过度兴奋的重要作用
EurekAlert!
Medical Xpress
Nature reviews neurology
Altmetric
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Li HH, SUNG HH, Lau CG#. Activation of somatostatin-expressing neuron in the lateral septum improves stress-induced depressive-like behaviors in mice. Pharmaceutics, 14(10):2253, 2022, https://www.mdpi.com/1999-4923/14/10/2253.
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Tsang T, He QL, Cohen EB, Stottrup C, Lien EC, Zhang HQ, Lau CG#, Chin YR#. Upregulation of receptor tyrosine kinase activity and stemness as resistance mechanisms to Akt inhibitors in breast cancer. Cancers, 14(20):5006, 2022, https://www.mdpi.com/2072-6694/14/20/5006.
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Ngo EFY*, Li HH*, Zhang HQ, Lau CG#. Acute fasting modulates food seeking behavior and neural signaling in the piriform cortex. Nutrients, 14(19):4156, 2022, https://www.mdpi.com/2072-6643/14/19/4156.
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Tian Y, Li J, Cheung TC, Tam V, Lau CG, Wang X, Chin YR#. Akt3 promotes cancer stemness in triple-negative breast cancer through YB1-Snail/Slug signaling axis. Genes and Diseases, 2022, https://www.sciencedirect.com/science/article/pii/S2352304222002276.
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Guo AN, Lau CG#. TNF-α orchestrates experience-dependent plasticity of excitatory and inhibitory synapses in the anterior piriform cortex, Frontiers in Neuroscience, 2022, https://www.frontiersin.org/articles/10.3389/fnins.2022.824454/full.
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Jiang HH, Guo AN, Chiu A, Li HH, Lai CSW, Lau CG#. Target-specific control of piriform cortical output via recruitment of distinct inhibitory circuits. FASEB J, 2021, https://faseb.onlinelibrary.wiley.com/doi/full/10.1096/fj.202100757R.
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Hu JY, Lai YN, Huang H, Ramakrishnan S, Pan Y, Ma VWS, Cheuk W, So GYK, He QL, Lau CG, Zhang L, Cho WCS, Chan KM, Wang X, Chin YR. TCOF1 upregulation in triple-negative breast cancer promotes stemness and tumor growth, and correlates with poor prognosis. British Journal of Cancer, https://www.nature.com/articles/s41416-021-01596-3, 2021.
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Lau CG#, Zhang HQ, Murthy VN#. Deletion of TrkB in parvalbumin interneurons alters cortical neural dynamics. Journal of Cellular Physiology, https://onlinelibrary.wiley.com/doi/10.1002/jcp.30571 , 2021.
# Co-corresponding authors.
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Huang YH, Jiang HH, Zheng QY, Fok AHK, Li XY, Lau CG, Lai CSW. Environmental enrichment or selective activation of parvalbumin-expressing interneurons ameliorates synaptic and behavioral deficits in schizophrenia animal models. Molecular Psychiatry, published online, 2021. https://www.nature.com/articles/s41380-020-01005-w
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Mazo C, Grimaud J, Shima Y, Murthy VN#, Lau CG#, Scientific Reports. Distinct projection patterns of different classes of layer 2 principal neurons in the olfactory cortex. , doi:10.1038/s41598-017-08331-0, 2017.
# Co-corresponding authors.
Before CityU
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Murphy JA*, Stein IS*, Lau CG, Peixoto R, Aman TK, Kaneko N, Aromolaran K, Saulnier JL, Popescu GK, Sabatini BL, Hell JW, Zukin RS. Phosphorylation of Ser1166 on GluN2B by PKA is critical to synaptic NMDA receptor function and Ca2+ signaling in spines. Journal of Neuroscience, 34:869-79, 2014.
* Equal first authors.
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Featured in This Week in The Journal.
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Lau CG, Murthy VN. Activity-dependent regulation of inhibition via GAD67. Journal of Neuroscience, 32:8521-31, 2012.
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Cover illustration.
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One of the most-read articles (#19) in June, 2012.
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Image of the week, BrainFacts.org.
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Lau CG, Takayasu Y, Rodenas-Ruano A, Paternain AV, Lerma J, Bennett MVL, Zukin RS. SNAP-25 is a target of PKC phosphorylation critical to NMDA receptor trafficking. Journal of Neuroscience, 30:242-254, 2010.
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Skeberdis VA*, Chevaleyre V*, Lau CG*, Goldberg JH, Pettit DL, Suadicani SO, Lin Y, Bennett MVL, Yuste R, Castillo PE, Zukin RS. Protein kinase A regulates calcium permeability of NMDA receptors. Nature Neuroscience, 9:501-510, 2006.
* Equal first authors.
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Rated 10 out of 10 and an “exceptional new finding” by James Bibb, Faculty of 1000 Biology, 2006.
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Featured in the Papers to Watch section of The Scientist, July, 2006.
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Featured in the Calcium Signaling and Neurobiology section, AfCS-Nature Signaling Gateway, Apr 2006.
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Ranked in the top 100 papers in ion channel research in 2006 by IonChannels.org. http://www.ionchannels.org/newsletters/ionchannels-2006-lit.html
Rewiews and textbook chapters
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Tetteh H, Lee M, Lau CG, Yang S, and (2017) Tinnitus: Prospects for pharmacological interventions with a seesaw model. The Neuroscientist, (Oct 9) doi: 10.1177/1073858417733415.
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Lau CG, Takeuchi K, Rodenas-Ruano A, Bennett MVL, Zukin RS. Regulation of NMDA receptor Ca2+ signalling and synaptic plasticity. Biochemical Society Transactions, 37:1369–1374, 2009.
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Lau CG, Zukin RS. NMDA receptor trafficking in synaptic plasticity and neuropsychiatric disorders. Nature Reviews Neuroscience, 8:413-416, 2007.
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Featured article of the June issue, 2007.
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Featured in the Signaling and Neurobiology sections, AfCS-Nature Signaling Gateway, June 2007.
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Zukin RS, Jover T, Yokota H, Calderone A, Simionescu M, Lau CG. Molecular and Cellular Mechanisms of Ischemia-induced Neuronal Death. In: Stroke: Pathophysiology, Diagnosis and Management. 4th Ed. Eds: Mohr, JP, Choi DW, Grotta JC, Weir B, Wolf PA. Philadelphia: Churchill Livingstone. pp. 829-854, 2004.