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Peer-reviewed articles

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     香港城市大学刘俊宇团队发现连接蛋白半通道抑制剂D4的抗抑郁样作用

  • Guo AN, Zhang HQ, Li HH, Chiu A, Garcia C, Lagos CF, Saez JC#, Lau CG#. Inhibition of connexin hemichannels alleviates neuroinflammation and hyperexcitability in temporal lobe epilepsy. Proc Natl Acad Sci USA, https://www.pnas.org/doi/10.1073/pnas.2213162119, 2022.

CityU neuroscientists discover a new drug candidate for treating epilepsy 
刘俊宇团队揭示连接蛋白半通道在减轻颞叶癫痫发病过程中的神经炎症和过度兴奋的重要作用
EurekAlert!
Medical Xpress
Nature reviews neurology
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  • Li HH, SUNG HH, Lau CG#. Activation of somatostatin-expressing neuron in the lateral septum improves stress-induced depressive-like behaviors in mice. Pharmaceutics, 14(10):2253, 2022, https://www.mdpi.com/1999-4923/14/10/2253.

  • Tsang T, He QL, Cohen EB, Stottrup C, Lien EC, Zhang HQ, Lau CG#, Chin YR#. Upregulation of receptor tyrosine kinase activity and stemness as resistance mechanisms to Akt inhibitors in breast cancer. Cancers, 14(20):5006, 2022, https://www.mdpi.com/2072-6694/14/20/5006.

 

  • Hu JY, Lai YN, Huang H, Ramakrishnan S, Pan Y, Ma VWS, Cheuk W, So GYK, He QL, Lau CG, Zhang L, Cho WCS, Chan KM, Wang X, Chin YR. TCOF1 upregulation in triple-negative breast cancer promotes stemness and tumor growth, and correlates with poor prognosis. British Journal of Cancer, https://www.nature.com/articles/s41416-021-01596-3, 2021.

      # Co-corresponding authors.

  • Mazo C, Grimaud J, Shima Y, Murthy VN#, Lau CG#, Scientific Reports. Distinct projection patterns of different classes of layer 2 principal neurons in the olfactory cortex. , doi:10.1038/s41598-017-08331-0, 2017.

     # Co-corresponding authors.

Before CityU

  • Murphy JA*, Stein IS*, Lau CG, Peixoto R, Aman TK, Kaneko N, Aromolaran K, Saulnier JL, Popescu GK, Sabatini BL, Hell JW, Zukin RS. Phosphorylation of Ser1166 on GluN2B by PKA is critical to synaptic NMDA receptor function and Ca2+ signaling in spines. Journal of Neuroscience, 34:869-79, 2014.

    * Equal first authors.

  • Featured in This Week in The Journal.

 

  • Lau CG, Murthy VN. Activity-dependent regulation of inhibition via GAD67. Journal of Neuroscience, 32:8521-31, 2012.

  • Cover illustration.

  • One of the most-read articles (#19) in June, 2012.

  • Image of the week, BrainFacts.org.

 

  • Lau CG, Takayasu Y, Rodenas-Ruano A, Paternain AV, Lerma J, Bennett MVL, Zukin RS. SNAP-25 is a target of PKC phosphorylation critical to NMDA receptor trafficking. Journal of Neuroscience, 30:242-254, 2010.

 

  • Skeberdis VA*, Chevaleyre V*, Lau CG*, Goldberg JH, Pettit DL, Suadicani SO, Lin Y, Bennett MVL, Yuste R, Castillo PE, Zukin RS. Protein kinase A regulates calcium permeability of NMDA receptors. Nature Neuroscience, 9:501-510, 2006.

    * Equal first authors.

 

Rewiews and textbook chapters

  • Tetteh H, Lee M, Lau CG, Yang S, and (2017) Tinnitus: Prospects for pharmacological interventions with a seesaw model. The Neuroscientist, (Oct 9) doi: 10.1177/1073858417733415.

  • Lau CG, Takeuchi K, Rodenas-Ruano A, Bennett MVL, Zukin RS. Regulation of NMDA receptor Ca2+ signalling and synaptic plasticity. Biochemical Society Transactions, 37:1369–1374, 2009.

 

  • Lau CG, Zukin RS. NMDA receptor trafficking in synaptic plasticity and neuropsychiatric disorders. Nature Reviews Neuroscience, 8:413-416, 2007.

  •   Featured article of the June issue, 2007.

  •    Featured in the Signaling and Neurobiology sections, AfCS-Nature Signaling Gateway, June 2007.

 

  • Zukin RS, Jover T, Yokota H, Calderone A, Simionescu M, Lau CG. Molecular and Cellular Mechanisms of Ischemia-induced Neuronal Death. In: Stroke: Pathophysiology, Diagnosis and Management. 4th Ed. Eds: Mohr, JP, Choi DW, Grotta JC, Weir B, Wolf PA. Philadelphia: Churchill Livingstone. pp. 829-854, 2004.

 

 

 

Publications

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